The Cultured Gut Reset™ Master Clinical Protocol is a proprietary, outcome-based functional medicine system designed to restore gut barrier integrity, calm immune activation, support detoxification pathways, and correct microbial imbalance only when clinically appropriate. This protocol is built around a fixed sequence with flexible pathways, establishing a repeatable clinical model where pathways change, but the sequence does not. It intentionally prioritizes physiologic terrain stabilization before diagnostic testing or antimicrobial intervention, ensuring improved patient tolerance, clearer laboratory data, and more durable outcomes. The Cultured Gut Reset™ Master Clinical Protocol is defined by a structured, multi-phase process that includes: • Early gut repair and immune calming before functional testing • Sequenced probiotic and prebiotic introduction based on tolerance • Layered detoxification support to prevent inflammatory or die-off reactions • Conditional use of antimicrobials guided by labs and clinical response • Temporary dietary restriction with intentional food reintroduction • Clear reassessment checkpoints and transition decision-making This system integrates clinical judgment, laboratory guidance, and patient education into a single, audit-ready framework that is easy to teach, easy to scale, and consistent across providers. It is delivered through a lab-inclusive medical membership model and is designed to serve as the foundational gut protocol for a wide range of gastrointestinal, immune, metabolic, and systemic conditions. The Cultured Gut Reset™ Master Clinical Protocol represents an original process, system, and clinical paradigm for gut restoration that replaces fragmented, test-first or kill-first approaches with a structured, physiology-first model of care.